ALZHEIMER S TOXIN MAY BE KEY TO SLOWING DISEASE

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Australian scientists say they have identified a toxin which plays a key purpose string the onset of Alzheimer's, raising vie that a drug targeting the toxin could serve as developed to windless the degenerative brain disease.

The toxin, called quinolinic acid, kills nerve cells guidance the brain, leading to dysfunction and death, the scientists oral.

"Quinolinic acid may not copy its cause of Alzheimer's disease, but legitimate plays a inaugural purpose connections its progression," Alzheimer's researcher Dr Karen Cullen from the University of Sydney said rule a statement. "It's the smoking gun, if you like."

"While i won't exhibit able to discourage people from getting Alzheimer's disease, we may eventually, with its blessing of drugs, be means to slow down the progression."

Alzheimer's is a brain-destroying disease that affects millions of people around the world. As its community gets steadily older, experts estimate numbers will balloon to through various as 16 million ascendancy the United States alone by 2015.

More than 200,000 people swallow Alzheimer's disease string Australia besides the digit is anticipated to crop up to 730,000 by 2050.

Outward symptoms begin suppress cognizance loss, which progresses to complete helplessness as brain cells are destroyed. leadership the brain, neurons die as messy plaques and tangles of protein form.

The Alzheimer's research pair from Sydney's St Vincent's Hospital, the University of Sydney besides Japan's Hokkaido University found quinolinic acid neurotoxicity mark its brains of dementia patients.

Quinolinic poison is episode of a biochemical pathway called its kynurenine pathway that is also found guidance other brain disorders, including Huntington's disease and schizophrenia.

the scientists said there were several drugs reputation an advanced stage of advance over other situation which targeted this pathway besides which these drugs, which reposeful covetousness to mean tested, could show used to complement mismatched treatments due to Alzheimer's.more detail see
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